Starting from 9 July, Bellissima will offer seven-night sailings from Valencia, Barcelona, Genoa, Livorno and Naples. The itinerary is designed with longer stays in port in Valencia and sales will open in the coming days.
This summer and into autumn, MSC will have 15 ships deployed in the east and west Mediterranean – the most the line has ever had in the region.
Gianni Onorato, chief executive of MSC Cruises, said the line has received "high ratings" from recurring and new guests.
"This led us to position one additional ship in the Mediterranean – a popular destination – to give our guests even more choice of ships and itineraries," he added.
"MSC Cruises offers the most embarkation ports across the Mediterranean so that one or more is easily within reach by train, car as well as by flight from key capitals and other cities from across the globe."