Harraghy is stepping down due to personal family reasons.
She will remain a consultant to Celebrity Cruises working behind the scenes to support the sales team in 2017.
Jo Rzymowska, managing director, Celebrity Cruises UK and Ireland said: “I would like to personally thank Sarah for all the positive impact she has had on our business.
“In the 15 months that Sarah was at the helm of our commercial sales function she has further enhanced our trade support efforts and ensured that our business is even more focused on key strategic partnerships.
“We have had one of our strongest ever years, and her impact on our business stands us in good stead for a great 2017.
"Our incredible team looks forward to working with her in a consultant capacity and we extend our support to her family."
Celebrity Cruises aims to announce a new head of its sales function in due course.
Celebrity Cruises was honoured at the recent TTG Travel Awards in September, winning LGBT Friendly Company of the Year, Luxury Specialist Cruise Line of the Year and Travel Company of the Year.
