The airport is adding new roles to meet the increased number of people and planes using the airport.
In November the airport passed 23 million passengers for the first time in its 77-year history.
Jobs on offer include: drivers, baggage handlers and receptionists.
Manchester Airport’s managing director, Ken O’Toole, said: “We are delighted that 2,500 jobs will be available across the airport site at the jobs fair in January 2016.
"Not only will these roles directly feed into, and increase, the 21,500 positions currently across the airport site, but they will also plug into the wider 45,000 jobs the airport indirectly supports across the region.”