The transport select committee said noise and pollution issues could be handled and should no longer be used as an excuse by politicians dragging their feet.
Instead they accused the government of procrastinating when they failed to settle the issue impartially by accepting the guidance of the independent panel when it published its own report before Christmas.
It had overwhelmingly recommended the additional capacity be built at Heathrow where £147 billion of economic benefits would be generated, as opposed to £89 billion at Gatwick.
A Heathrow spokesman welcomed the report, adding: "The real, independent evidence continues to point towards Heathrow. The transport committee and the prime minister’s airports commission have confirmed that an expanded Heathrow will be an economic powerhouse driving jobs creation across the UK and fuelling a boom in British exports.
“Families and businesses across the nation are counting on the prime minister to secure Britain’s long term future. Only an expanded Heathrow delivers and now is the time to make it happen.”
However, a Gatwick spokesperson argued: "The transport committee’s astonishing statement that the arguments ‘for and against airport expansion have changed little in a quarter of a century’ ignores the significant change within the aviation industry following the break-up of the BAA monopoly in 2009 and the worsening of air quality in the UK which has repeatedly halted Heathrow’s plans in the past.
“In one key respect, however, the committee is right to say that nothing has changed - Heathrow is still undeliverable. Fortunately, there is now a credible alternative at Gatwick that can mean Britain finally gets on with it.
“The opportunity to end decades of delay and false starts can only be achieved by giving the green light for Gatwick expansion.
"Gatwick is the only scheme which can actually deliver the economic benefits airport expansion would bring without the dramatic and unacceptable impacts on noise and air quality.”