The line said the momentum in sales is the result of a "strong, established relationship" with its trade partners and continued investment in its brand profile.
MSC has seen a "significant" increase in bookings from high street agents, homeworkers, independent businesses, tour operators and consolidators, as well as large cruise specialists continuing to perform "exceptionally".
Steve Williams, director of sales for MSC Cruises, said it was "so rewarding" to see the trade supporting MSC at levels "never experienced previously" with sales at an all-time high.
"We are seeing unprecedented levels of support from all our trade partners, and for this we would like to extend our thanks," he added.
MSC has four ships committed to the UK market in 2022 and 2023 – Magnifica for the 2022 winter/spring season, Virtuosa for the summer, Preziosa for the winter and Grandiosa for summer 2023.