Prices for one-way tickets to Los Angeles and San Francisco via Reykjavik start from £139.
The Los Angeles route will operate four times a week starting on June 15 while San Francisco will join the network on June 9 offering five weekly flights.
Skuli Mogensen, founder and chief executive of Wow air, said: “The addition of Los Angeles and San Francisco to our rapidly expanding network is a game changer for Wow air as we cement ourselves as the industry leader in the ultra-low-cost long haul category.
"We always aim to be the cheapest flight provider on the routes we fly to and with the £139 fare between the UK and California we have accomplished this once again."
Wow air launched flights to Boston and Washington DC early last year and will fly to Montreal and Toronto from May.
