The twice weekly flight launches on December 1 and will operate on Tuesdays and Saturdays on board an Airbus A319 with 28 business class seats.
Edinburgh airport chief executive Gordon Dewar said: "Edinburgh’s Christmas has a flavour of Germany with its own German markets but what a fantastic opportunity to get away and experience it first-hand in Munich with the launch of this winter route.
“We have great connections to Munich and this of course opens up other areas in Central and Eastern Europe thanks to the hub connectivity, and that’s what we want to offer passengers – greater choice and travel flexibility."
