The airline said it had more than 3,000 first aid trained and security cleared staff up and down the country ready to assist.
"Furloughed crew have an ideal skill set to be able to assist in the effort to provide much needed inoculation support to the NHS in rolling out the Covid-19 vaccine," said easyJet.
Those fast-tracked to assist will undergo online training followed by on-site immunisation training to become full-qualified vaccinators.
Last year, easyJet crew came forward to support the NHS Nightingale hospitals and volunteer as NHS responders.
Meanwhile, through Project Wingman, easyJet staff provided wellbeing support to frontline medical staff in 85 countries across the country.
EasyJet expects hundreds of volunteers to answer the call and come come forward again to assist the vaccination programme.
Elliot Howard-Jones, chief executive of Hertfordshire Community NHS Trust, one of the first to enlist the support of fast-tracked easyJet crew, added: “We are all looking forward to welcoming some of first easyJet crew for further training to become highly-valued members of our trust’s immunisation team.
"Their first aid and caring skills will make them ideally suited to help deliver the huge task we currently face, to give those most at risk protection against the Covid-19 virus."
Luton-based Katy Bryant, who has been a member of easyJet cabin crew since 2005, is among those to have applied to become a vaccinator.
"Like everyone, I’m incredibly grateful to our NHS and all frontline healthcare workers for all they continue to do for the country with the continued pressure they are facing from the virus, so when the opportunity came for cabin crew to assist the NHS as vaccinators, I knew I wanted to apply," she said.
“As cabin crew, we are in a great position to support the vaccination effort because of the first aid and safety-focused training we receive for our job. I’m sure I will be joined by many of my fellow cabin crew at easyJet who will want to support the NHS in the vital roll-out of the vaccine across the country.”
Vaccine ’key to unlocking travel’
EasyJet chief executive Johan Lundgren said he was sure the airline’s cabin crew would step up once again to help.
“The progress the country is making on the vaccination programme is an exciting and much-needed development," said Lundgren.
"Once rolled out, it will enable normal life to return and is undoubtedly the key to unlocking travel again and enabling travel for work, to visit friends and family or for a much-needed holiday.
“We are pleased and proud to be able to play our part and stand by ready to support wherever else we can.”
