The non-stop route will recommence on 17 July 2021.
Initially, the flight will operate three times weekly with an A350-900 aircraft but it is hoped that in time this can gradually increase and also include the return of the westbound transatlantic connection to Houston, US.
Mohamed Rafi Mar, general manager, UK and Ireland, said: “Manchester and the northwest region have been a key part of our route network for over 30 years, so while it was never our intention to have an enforced break in service as has happened due to the unprecedented Covid-19 pandemic, we are delighted to be able to make our return.
“As restrictions slowly ease, our dedicated Manchester staff are excited to welcome our customers back once more and we look forward to continuing our longstanding and deep connection with the city of Manchester and its surroundings.”